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Asymmetric Total Synthesis of Pyranicin

[Image: see text] The asymmetric total synthesis of pyranicin (1) is reported. The butenolide ring was constructed via an asymmetric alkylation/ring-closing metathesis strategy. The three stereocenters in the left-hand tetrahydropyran ring were installed by sequential chiral auxiliary-mediated aldol...

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Detalhes bibliográficos
Main Authors: Crimmins, Michael T., Jacobs, Danielle L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826115/
https://ncbi.nlm.nih.gov/pubmed/19438254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol900814w
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