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Total Synthesis of Apoptolidin A

[Image: see text] A highly convergent, enantioselective total synthesis of the potent antitumor agent apoptolidin A, has been completed. The key transformations include highly selective glycosylations to attach the C27 disaccharide and the C9 6′-deoxy-l-glucose, a cross metathesis to incorporate the...

詳細記述

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書誌詳細
主要な著者: Crimmins, Michael T., Christie, Hamish S., Long, Alan, Chaudhary, Kleem
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653204/
https://ncbi.nlm.nih.gov/pubmed/19199767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802829n
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