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Total Synthesis of Apoptolidin A

[Image: see text] A highly convergent, enantioselective total synthesis of the potent antitumor agent apoptolidin A, has been completed. The key transformations include highly selective glycosylations to attach the C27 disaccharide and the C9 6′-deoxy-l-glucose, a cross metathesis to incorporate the...

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Detalhes bibliográficos
Main Authors: Crimmins, Michael T., Christie, Hamish S., Long, Alan, Chaudhary, Kleem
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653204/
https://ncbi.nlm.nih.gov/pubmed/19199767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802829n
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