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Evolution of the HIV-1 env Gene in the Rag2(−/−) γ(C)(−/−) Humanized Mouse Model
Rag2(−/−) γ(C)(−/−) mice transplanted with human hematopoietic stem cells (DKO-hu-HSC mice) mimic aspects of human infection with human immunodeficiency virus type 1 (HIV-1), including sustained viral replication and CD4(+) T-cell decline. However, the extent of HIV-1 evolution during long-term infe...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826074/ https://ncbi.nlm.nih.gov/pubmed/20042504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02180-09 |
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