Pharmacokinetics of Chloroquine and Monodesethylchloroquine in Pregnancy

In order to determine the pharmacokinetic disposition of chloroquine (CQ) and its active metabolite, desethylchloroquine (DECQ), when administered as intermittent presumptive treatment in pregnancy (IPTp) for malaria, 30 Papua New Guinean women in the second or third trimester of pregnancy and 30 ag...

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Main Authors: Karunajeewa, Harin A., Salman, Sam, Mueller, Ivo, Baiwog, Francisca, Gomorrai, Servina, Law, Irwin, Page-Sharp, Madhu, Rogerson, Stephen, Siba, Peter, Ilett, Kenneth F., Davis, Timothy M. E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825967/
https://ncbi.nlm.nih.gov/pubmed/20086162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01269-09
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