Optimal Antimalarial Dose Regimens for Sulfadoxine-Pyrimethamine with or without Azithromycin in Pregnancy Based on Population Pharmacokinetic Modeling

Optimal dosing of sulfadoxine-pyrimethamine (SP) as intermittent preventive treatment in pregnancy remains to be established, particularly when coadministered with azithromycin (AZI). To further characterize SP pharmacokinetics in pregnancy, plasma concentration-time data from 45 nonpregnant and 45...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Salman, Sam, Baiwog, Francisca, Page-Sharp, Madhu, Griffin, Susan, Karunajeewa, Harin A., Mueller, Ivo, Rogerson, Stephen J., Siba, Peter M., Ilett, Kenneth F., Davis, Timothy M. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404578/
https://ncbi.nlm.nih.gov/pubmed/28242669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02291-16
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