Immunization with a Combination of Three Pneumococcal Proteins Confers Additive and Broad Protection against Streptococcus pneumoniae Infections in Mice

Pneumococcal polysaccharide-based vaccines are effective in preventing pneumococcus infection; however, some drawbacks preclude their widespread use in developing and undeveloped countries. Here, we evaluated the protective effects of ATP-dependent caseinolytic protease (ClpP), pneumolysin mutant (Δ...

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Autors principals: Wu, Kaifeng, Zhang, Xuemei, Shi, Jing, Li, Nan, Li, Dairong, Luo, Miao, Cao, Ju, Yin, Nanlin, Wang, Hong, Xu, Wenchun, He, Yujuan, Yin, Yibing
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825939/
https://ncbi.nlm.nih.gov/pubmed/20038538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00473-09
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