Shiga Toxin 1-Induced Inflammatory Response in Lipopolysaccharide-Sensitized Astrocytes Is Mediated by Endogenous Tumor Necrosis Factor Alpha

Hemolytic-uremic syndrome (HUS) is generally caused by Shiga toxin (Stx)-producing Escherichia coli. Endothelial dysfunction mediated by Stx is a central aspect in HUS development. However, inflammatory mediators such as bacterial lipopolysaccharide (LPS) and polymorphonuclear neutrophils (PMN) cont...

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Bibliographische Detailangaben
Hauptverfasser: Landoni, Verónica I., de Campos-Nebel, Marcelo, Schierloh, Pablo, Calatayud, Cecilia, Fernandez, Gabriela C., Ramos, M. Victoria, Rearte, Bárbara, Palermo, Marina S., Isturiz, Martín A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825925/
https://ncbi.nlm.nih.gov/pubmed/20008539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00932-09
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