Shiga Toxin 1 Induces on Lipopolysaccharide-Treated Astrocytes the Release of Tumor Necrosis Factor-alpha that Alter Brain-Like Endothelium Integrity

The hemolytic uremic syndrome (HUS) is characterized by hemolytic anemia, thrombocytopenia and renal dysfunction. The typical form of HUS is generally associated with infections by Gram-negative Shiga toxin (Stx)-producing Escherichia coli (STEC). Endothelial dysfunction induced by Stx is central, b...

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Detalhes bibliográficos
Main Authors: Landoni, Verónica I., Schierloh, Pablo, de Campos Nebel, Marcelo, Fernández, Gabriela C., Calatayud, Cecilia, Lapponi, María J., Isturiz, Martín A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315494/
https://ncbi.nlm.nih.gov/pubmed/22479186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002632
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