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Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
Viruses rely on the metabolic network of their cellular hosts to provide energy and building blocks for viral replication. We developed a flux measurement approach based on liquid chromatography–tandem mass spectrometry to quantify changes in metabolic activity induced by human cytomegalovirus (HCMV...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825756/ https://ncbi.nlm.nih.gov/pubmed/18820684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1500 |
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