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EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis
Background information. The BOR (branchio-oto-renal) syndrome is a dominant disorder most commonly caused by mutations in the EYA1 (Eyes Absent 1) gene. Symptoms commonly include deafness and renal anomalies. Results. We have used the embryos of the frog Xenopus laevis as an animal model for early e...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825735/ https://ncbi.nlm.nih.gov/pubmed/19951260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BC20090098 |
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