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EYA1 mutations associated with the branchio-oto-renal syndrome result in defective otic development in Xenopus laevis

Background information. The BOR (branchio-oto-renal) syndrome is a dominant disorder most commonly caused by mutations in the EYA1 (Eyes Absent 1) gene. Symptoms commonly include deafness and renal anomalies. Results. We have used the embryos of the frog Xenopus laevis as an animal model for early e...

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Detalhes bibliográficos
Main Authors: Li, Youe, Manaligod, Jose M., Weeks, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825735/
https://ncbi.nlm.nih.gov/pubmed/19951260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BC20090098
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