Reciprocal regulation of microRNA-1 and IGF-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions

BACKGROUND: MicroRNAs (miRNAs/miRs) are small conserved RNA molecules of 22 nucleotides, which negatively modulate gene expression primarily through base paring to the 3′ untranslated region (UTR) of target mRNAs. The muscle-specific miR-1 has been implicated in cardiac hypertrophy, heart developmen...

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Bibliografiset tiedot
Päätekijät: Elia, Leonardo, Contu, Riccardo, Quintavalle, Manuela, Varrone, Francesca, Chimenti, Cristina, Russo, Matteo Antonio, Cimino, Vincenzo, De Marinis, Laura, Frustaci, Andrea, Catalucci, Daniele, Condorelli, Gianluigi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825656/
https://ncbi.nlm.nih.gov/pubmed/19933931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.879429
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