The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

Mechanisms controlling vascular smooth muscle cell (VSMC) plasticity and renewal still remain to be completely elucidated. A class of small RNAs called microRNAs (miRs) regulate gene expression at the post-transcriptional level. Here we demonstrate a critical role of the miR-143/145 cluster in SMC d...

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Main Authors: Elia, Leonardo, Quintavalle, Manuela, Zhang, Jianlin, Contu, Riccardo, Cossu, Luca, Latronico, Michael V. G., Peterson, Kirk L., Indolfi, Ciro, Catalucci, Daniele, Chen, Ju, Courtneidge, Sara A., Condorelli, Gianluigi
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014107/
https://ncbi.nlm.nih.gov/pubmed/19816508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2009.153
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