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Reciprocal regulation of microRNA-1 and IGF-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions
BACKGROUND: MicroRNAs (miRNAs/miRs) are small conserved RNA molecules of 22 nucleotides, which negatively modulate gene expression primarily through base paring to the 3′ untranslated region (UTR) of target mRNAs. The muscle-specific miR-1 has been implicated in cardiac hypertrophy, heart developmen...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825656/ https://ncbi.nlm.nih.gov/pubmed/19933931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.879429 |
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