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Site-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: Protein carbonylation is diminished by ascorbic acid

The protein targets and sites of modification by 4-hydroxy-2(E)-nonenal (HNE) in human monocytic THP-1 cells after exogenous exposure to HNE were examined using a multi-pronged proteomic approach involving electrophoretic, immunoblotting and mass spectrometric methods. Immunoblot analysis using mono...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chavez, Juan, Chung, Woon-Gye, Miranda, Cristobal L., Singhal, Mudita, Stevens, Jan F., Maier, Claudia S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825578/
https://ncbi.nlm.nih.gov/pubmed/20043646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9002462
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