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Ascorbic Acid Promotes Detoxification and Elimination of 4-Hydroxy-2(E)-nonenal in Human Monocytic THP-1 Cells

4-Hydroxy-2(E)-nonenal (HNE), a reactive aldehyde derived from oxidized lipids, has been implicated in the pathogenesis of cardiovascular and neurological diseases, in part by its ability to induce oxidative stress and by protein carbonylation in target cells. The effects of intracellular ascorbic a...

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Autori principali: Miranda, Cristobal L., Reed, Ralph L., Kuiper, Heather C., Alber, Susan, Stevens, Jan F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730585/
https://ncbi.nlm.nih.gov/pubmed/19326901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900042u
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