N-terminal Extension of the Cholera Toxin A1-chain Causes Rapid Degradation after Retrotranslocation from Endoplasmic Reticulum to Cytosol

Cholera toxin travels from the plasma membrane to the endoplasmic reticulum of host cells, where a portion of the toxin, the A1-chain, is unfolded and targeted to a protein-conducting channel for retrotranslocation to the cytosol. Unlike most retrotranslocation substrates, the A1-chain escapes degra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wernick, Naomi L. B., De Luca, Heidi, Kam, Wendy R., Lencer, Wayne I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2010
Gaiak:
Protein Synthesis and Degradation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825409/
https://ncbi.nlm.nih.gov/pubmed/20056601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.062067
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak