Loading...

CRTAP deficiency leads to abnormally high bone matrix mineralization in a murine model and in children with Osteogenesis Imperfecta type VII

Cartilage-associated protein (CRTAP) is an essential cofactor for the proper post-translational chain modification and collagen folding. CRTAP mutations lead in mice (Crtap−/− mice) and humans (OI type VII) to a severe/lethal osteochondrodystrophy; patients have fractures at birth, deformities of th...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Fratzl-Zelman, N, Morello, R., Lee, B, Rauch, F, Glorieux, FH, Misof, BM, Klaushofer, K, Roschger, P
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825377/
https://ncbi.nlm.nih.gov/pubmed/19895918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2009.10.037
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!