CXCR4/SDF1 mediate hypoxia induced chondrosarcoma cell invasion through ERK signaling and increased MMP1 expression

BACKGROUND: Chondrosarcoma is a disease that does not respond to conventional cytotoxic chemotherapy and expression of MMP1 is a marker for a poor prognosis. The mechanism of increased MMP1 expression in chondrosarcoma is not completely known. Our goal is to identify molecular pathways that could se...

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Main Authors: Sun, Xiaojuan, Wei, Lei, Chen, Qian, Terek, Richard M
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2010
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825244/
https://ncbi.nlm.nih.gov/pubmed/20102637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-17
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