SIRT2 Promotes the Migration and Invasion of Gastric Cancer through RAS/ERK/JNK/MMP-9 Pathway by Increasing PEPCK1-Related Metabolism()()

Metastasis is the most important feature of gastric cancer (GC) and the most widely recognized reason for GC-related deaths. Unfortunately, the underlying mechanism behind this metastasis remains unknown. Mounting evidence suggests the dynamic regulatory role of sirtuin2 (SIRT2), a histone deacetyla...

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Pubblicato in:Neoplasia
Autori principali: Li, Yang, Zhang, Mingming, Dorfman, Robert G., Pan, Yida, Tang, Dehua, Xu, Lei, Zhao, Zhenguo, Zhou, Qian, Zhou, Lixing, Wang, Yuming, Yin, Yuyao, Shen, Shanshan, Kong, Bo, Friess, Helmut, Zhao, Shimin, Wang, Lei, Zou, Xiaoping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press 2018
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Original article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005814/
https://ncbi.nlm.nih.gov/pubmed/29925042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.03.008
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