Formation of GW/P bodies as marker for microRNA-mediated regulation of innate immune signaling in THP-1 cells

GW bodies (GWB, or P bodies) are cytoplasmic foci thought to result from microRNA (miRNA) regulation of mRNA targets and subsequent mRNA degradation. The purpose of this study is to examine the effects of lipopolysaccharide (LPS) stimulation of human monocytes on GW body formation, miRNA induction,...

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Detalhes bibliográficos
Main Authors: Pauley, Kaleb M., Satoh, Minoru, Pauley, Brad A., Dominguez-Gutierrez, Paul R., Wallet, Shannon M., Holliday, L. Shannon, Cha, Seunghee, Reeves, Westley H., Chan, Edward K.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824770/
https://ncbi.nlm.nih.gov/pubmed/19918258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2009.84
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