Formation of GW/P bodies as marker for microRNA-mediated regulation of innate immune signaling in THP-1 cells

GW bodies (GWB, or P bodies) are cytoplasmic foci thought to result from microRNA (miRNA) regulation of mRNA targets and subsequent mRNA degradation. The purpose of this study is to examine the effects of lipopolysaccharide (LPS) stimulation of human monocytes on GW body formation, miRNA induction,...

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Autors principals: Pauley, Kaleb M., Satoh, Minoru, Pauley, Brad A., Dominguez-Gutierrez, Paul R., Wallet, Shannon M., Holliday, L. Shannon, Cha, Seunghee, Reeves, Westley H., Chan, Edward K.L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824770/
https://ncbi.nlm.nih.gov/pubmed/19918258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2009.84
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