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Detection of the Argonaute Protein Ago2 and microRNAs in the RNA Induced Silencing Complex (RISC) Using a Monoclonal Antibody

MicroRNAs (miRNAs) are short RNA molecules responsible for post-transcriptional gene silencing by the degradation or translational inhibition of their target messenger RNAs (mRNAs). This process of gene silencing, known as RNA interference (RNAi), is mediated by highly conserved Argonaute (Ago) prot...

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Detalhes bibliográficos
Main Authors: Ikeda, Keigo, Satoh, Minoru, Pauley, Kaleb M., Fritzler, Marvin J., Reeves, Westley H., Chan, Edward K.L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1913063/
https://ncbi.nlm.nih.gov/pubmed/17054975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2006.09.010
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