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Identification of GW182 and its novel isoform TNGW1 as translational repressors in Ago2-mediated silencing

RNA interference is triggered by small interfering RNA and microRNA, and is a potent mechanism in post-transcriptional regulation for gene expression. GW182 (also known as TNRC6A), an 182-kDa protein encoded by TNRC6A, is important for this process, although details of its function remain unclear. H...

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Publicat a:J Cell Sci
Autors principals: Li, Songqing, Lian, Shang L., Moser, Joanna J., Fritzler, Mark L., Fritzler, Marvin J., Satoh, Minoru, Chan, Edward K. L.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695043/
https://ncbi.nlm.nih.gov/pubmed/19056672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.036905
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