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O-Acylation of Hydroxyproline Residues: Effect on Peptide Bond Isomerization and Collagen Stability
In collagen, strands of sequence XaaYaaGly form a triple helical structure. The Yaa residue is often (2S,4R)-4-hydroxyproline (Hyp). The inductive effect of the hydroxyl group of Hyp residues greatly increases collagen stability. Here, electron withdrawal by the hydroxyl group in Hyp and its 4S dias...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824568/ https://ncbi.nlm.nih.gov/pubmed/15558658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.20164 |
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