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The Aberrance of the 4S Diastereomer of 4-Hydroxyproline

Prolyl 4-hydroxylases install a hydroxyl group in the 4R configuration on the γ-carbon atom of certain (2S)-proline (Pro) residues in tropocollagen, elastin, and other proteins and other proteins to form (2S,4R)-4-hydroxyproline (Hyp). The gauche effect arising from this prevalent post-translational...

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Main Authors: Shoulders, Matthew D., Kotch, Frank W., Choudhary, Amit, Guzei, Ilia A., Raines, Ronald T.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931826/
https://ncbi.nlm.nih.gov/pubmed/20681719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103082y
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