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4-Chloroprolines: Synthesis, Conformational Analysis, and Effect on the Collagen Triple Helix
Collagen is an abundant, triple-helical protein comprising three strands of the repeating sequence: Xaa–Yaa–Gly. (2S)-Proline and (2S,4R)-4-hydroxyproline (Hyp) are common in the primary structure of collagen. Here, we use nonnatural proline derivatives to reveal determinants of collagen stability....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802577/ https://ncbi.nlm.nih.gov/pubmed/17937398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.20864 |
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