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4-Chloroprolines: Synthesis, Conformational Analysis, and Effect on the Collagen Triple Helix

Collagen is an abundant, triple-helical protein comprising three strands of the repeating sequence: Xaa–Yaa–Gly. (2S)-Proline and (2S,4R)-4-hydroxyproline (Hyp) are common in the primary structure of collagen. Here, we use nonnatural proline derivatives to reveal determinants of collagen stability....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Shoulders, Matthew D., Guzei, Ilia A., Raines, Ronald T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802577/
https://ncbi.nlm.nih.gov/pubmed/17937398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.20864
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