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Comparative effects of H(+) and Ca(2+) on large-conductance Ca(2+)- and voltage-gated Slo1 K(+) channels

Large-conductance Ca(2+)- and voltage-gated Slo1 BK channels are allosterically activated by depolarization and intracellular ligands such as Ca(2+). Of the two high-affinity Ca(2+) sensors present in the channel, the RCK1 sensor also mediates H(+)-dependent activation of the channel. In this study,...

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Detalhes bibliográficos
Main Authors: Hou, Shangwei, Horrigan, Frank T., Xu, Rong, Heinemann, Stefan H., Hoshi, Toshinori
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824562/
https://ncbi.nlm.nih.gov/pubmed/19617704
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