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Absence of Deleterious Palladin Mutations in Patients with Familial Pancreatic Cancer

It has been reported that germline mutations in the palladin gene (PALLD) cause the familial aggregation of pancreatic cancer, but the evidence is weak and controversial. We sequenced the coding regions of PALLD in 48 individuals with familial pancreatic cancer. We did not find any deleterious mutat...

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Detalhes bibliográficos
Main Authors: Klein, Alison P., Borges, Michael, Griffith, Margaret, Brune, Kieran, Hong, Seung-Mo, Omura, Noriyuki, Hruban, Ralph H., Goggins, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824557/
https://ncbi.nlm.nih.gov/pubmed/19336541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0056
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