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Absence of Deleterious Palladin Mutations in Patients with Familial Pancreatic Cancer

It has been reported that germline mutations in the palladin gene (PALLD) cause the familial aggregation of pancreatic cancer, but the evidence is weak and controversial. We sequenced the coding regions of PALLD in 48 individuals with familial pancreatic cancer. We did not find any deleterious mutat...

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Hlavní autoři: Klein, Alison P., Borges, Michael, Griffith, Margaret, Brune, Kieran, Hong, Seung-Mo, Omura, Noriyuki, Hruban, Ralph H., Goggins, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824557/
https://ncbi.nlm.nih.gov/pubmed/19336541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0056
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