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Absence of Deleterious Palladin Mutations in Patients with Familial Pancreatic Cancer

It has been reported that germline mutations in the palladin gene (PALLD) cause the familial aggregation of pancreatic cancer, but the evidence is weak and controversial. We sequenced the coding regions of PALLD in 48 individuals with familial pancreatic cancer. We did not find any deleterious mutat...

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Main Authors: Klein, Alison P., Borges, Michael, Griffith, Margaret, Brune, Kieran, Hong, Seung-Mo, Omura, Noriyuki, Hruban, Ralph H., Goggins, Michael
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824557/
https://ncbi.nlm.nih.gov/pubmed/19336541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0056
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