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Absence of germline BRCA1 mutations in Familial Pancreatic Cancer Patients

Recent studies have suggested that germ line mutations in the BRCA1 gene may confer an increased risk of developing pancreatic cancer. To determine if BRCA1 mutations explain a significant proportion of familial pancreatic cancer, we sequenced the BRCA1 gene in a large series of well-characterized p...

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Detalhes bibliográficos
Main Authors: Axilbund, Jennifer E., Argani, Pedram, Kamiyama, Mihoko, Palmisano, Emily, Raben, Marian, Borges, Michael, Brune, Kieran A., Goggins, Michael, Hruban, Ralph H., Klein, Alison P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684337/
https://ncbi.nlm.nih.gov/pubmed/19029836
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