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Salt Dependence of IRF1 DBD Binding to DNA Reveals Ions Are Localized Around Protein and DNA
The equilibrium dissociation constant of the DNA binding domain of interferon regulatory factor 1, IRF1 DBD, for its DNA binding site depends strongly on salt concentration and salt type. These dependencies are consistent with IRF1 DBD binding to DNA resulting in cation release from the DNA and both...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824552/ https://ncbi.nlm.nih.gov/pubmed/18324782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi702082q |
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