Regulation of ploidy and senescence by the AMPK-related kinase NUAK1

Senescence is an irreversible cell-cycle arrest that is elicited by a wide range of factors, including replicative exhaustion. Emerging evidences suggest that cellular senescence contributes to ageing and acts as a tumour suppressor mechanism. To identify novel genes regulating senescence, we perfor...

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Main Authors: Humbert, Nicolas, Navaratnam, Naveenan, Augert, Arnaud, Da Costa, Marco, Martien, Sébastien, Wang, Jing, Martinez, Dolores, Abbadie, Corinne, Carling, David, de Launoit, Yvan, Gil, Jesus, Bernard, David
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824453/
https://ncbi.nlm.nih.gov/pubmed/19927127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.342
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