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The M-type receptor PLA2R regulates senescence through the p53 pathway

Senescence is a stable proliferative arrest induced by various stresses such as telomere erosion, oncogenic or oxidative stress. Compelling evidence suggests that it acts as a barrier against tumour development. Describing new mechanisms that favour an escape from senescence can thus reveal new insi...

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Bibliografiska uppgifter
Huvudupphovsmän: Augert, Arnaud, Payré, Christine, de Launoit, Yvan, Gil, Jesus, Lambeau, Gérard, Bernard, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658567/
https://ncbi.nlm.nih.gov/pubmed/19197340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.255
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