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Regulation of ploidy and senescence by the AMPK-related kinase NUAK1
Senescence is an irreversible cell-cycle arrest that is elicited by a wide range of factors, including replicative exhaustion. Emerging evidences suggest that cellular senescence contributes to ageing and acts as a tumour suppressor mechanism. To identify novel genes regulating senescence, we perfor...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824453/ https://ncbi.nlm.nih.gov/pubmed/19927127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.342 |
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