Recruitment of CREB1 and Histone Deacetylase 2 (HDAC2) to the Mouse Ltbp-1 Promoter Regulates its Constitutive Expression in a Dioxin Receptor-dependent Manner

Latent TGFβ-binding protein 1 (LTBP-1) is a key regulator of TGFβ targeting and activation in the extracellular matrix. LTBP-1 is recognized as a major docking molecule to localize, and possibly to activate, TGFβ in the extracellular matrix. Despite this relevant function, the molecular mechanisms r...

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Bibliographische Detailangaben
Hauptverfasser: Gomez-Duran, Aurea, Ballestar, Esteban, Carvajal-Gonzalez, Jose M., Marlowe, Jennifer L., Puga, Alvaro, Esteller, Manel, Fernandez-Salguero, Pedro M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824431/
https://ncbi.nlm.nih.gov/pubmed/18508077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.04.056
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