Blueprint for antimicrobial hit discovery targeting metabolic networks

Advances in genome analysis, network biology, and computational chemistry have the potential to revolutionize drug discovery by combining system-level identification of drug targets with the atomistic modeling of small molecules capable of modulating their activity. To demonstrate the effectiveness...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shen, Y., Liu, J., Estiu, G., Isin, B., Ahn, Y-Y., Lee, D-S., Barabási, A-L., Kapatral, V., Wiest, O., Oltvai, Z. N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824290/
https://ncbi.nlm.nih.gov/pubmed/20080587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909181107
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