Comparative Genome-Scale Metabolic Reconstruction and Flux Balance Analysis of Multiple Staphylococcus aureus Genomes Identify Novel Antimicrobial Drug Targets

Mortality due to multidrug-resistant Staphylococcus aureus infection is predicted to surpass that of human immunodeficiency virus/AIDS in the United States. Despite the various treatment options for S. aureus infections, it remains a major hospital- and community-acquired opportunistic pathogen. Wit...

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Hlavní autoři: Lee, Deok-Sun, Burd, Henry, Liu, Jiangxia, Almaas, Eivind, Wiest, Olaf, Barabási, Albert-László, Oltvai, Zoltán N., Kapatral, Vinayak
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
Computational Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698402/
https://ncbi.nlm.nih.gov/pubmed/19376871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01743-08
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