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Blueprint for antimicrobial hit discovery targeting metabolic networks
Advances in genome analysis, network biology, and computational chemistry have the potential to revolutionize drug discovery by combining system-level identification of drug targets with the atomistic modeling of small molecules capable of modulating their activity. To demonstrate the effectiveness...
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| Auteurs principaux: | , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2824290/ https://ncbi.nlm.nih.gov/pubmed/20080587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909181107 |
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