Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility

The viral spike of HIV-1 is composed of three gp120 envelope glycoproteins attached noncovalently to three gp41 transmembrane molecules. Viral entry is initiated by binding to the CD4 receptor on the cell surface, which induces large conformational changes in gp120. These changes not only provide a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Pancera, Marie, Majeed, Shahzad, Ban, Yih-En Andrew, Chen, Lei, Huang, Chih-chin, Kong, Leopold, Kwon, Young Do, Stuckey, Jonathan, Zhou, Tongqing, Robinson, James E., Schief, William R., Sodroski, Joseph, Wyatt, Richard, Kwong, Peter D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824281/
https://ncbi.nlm.nih.gov/pubmed/20080564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911004107
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk