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Probing the reaction mechanism of IspH protein by x-ray structure analysis

Isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) represent the two central intermediates in the biosynthesis of isoprenoids. The recently discovered deoxyxylulose 5-phosphate pathway generates a mixture of IPP and DMAPP in its final step by reductive dehydroxylation of 1-hydroxy-2...

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Autori principali: Gräwert, Tobias, Span, Ingrid, Eisenreich, Wolfgang, Rohdich, Felix, Eppinger, Jörg, Bacher, Adelbert, Groll, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824267/
https://ncbi.nlm.nih.gov/pubmed/20080550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913045107
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