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Metabolic Acetate Therapy for the Treatment of Traumatic Brain Injury

Patients suffering from traumatic brain injury (TBI) have decreased markers of energy metabolism, including N-acetylaspartate (NAA) and ATP. In the nervous system, NAA-derived acetate provides acetyl-CoA required for myelin lipid synthesis. Acetate can also be oxidized in mitochondria for the deriva...

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Autors principals: Arun, Peethambaran, Ariyannur, Prasanth S., Moffett, John R., Xing, Guoqiang, Hamilton, Kristen, Grunberg, Neil E., Ives, John A., Namboodiri, Aryan M.A.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824219/
https://ncbi.nlm.nih.gov/pubmed/19803785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2009.0994
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