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Formulation and coating of microneedles with inactivated influenza virus to improve vaccine stability and immunogenicity

Microneedle patches coated with solid-state influenza vaccine have been developed to improve vaccine efficacy and patient coverage. However, dip coating microneedles with influenza vaccine can reduce antigen activity. In this study, we sought to determine the experimental factors and mechanistic pat...

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Detalhes bibliográficos
Main Authors: Kim, Yeu-Chun, Quan, Fu-Shi, Compans, Richard W., Kang, Sang-Moo, Prausnitz, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823933/
https://ncbi.nlm.nih.gov/pubmed/19840825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.10.013
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