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Stability Kinetics of Influenza Vaccine Coated onto Microneedles During Drying and Storage

PURPOSE: This study sought to determine the effects of microneedle coating formulation, drying time and storage time on antigen stability and in vivo immunogenicity of influenza microneedle vaccines. METHODS: The stability of inactivated influenza virus vaccine was monitored by hemagglutination (HA)...

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Detalhes bibliográficos
Main Authors: Kim, Yeu-Chun, Quan, Fu-Shi, Compans, Richard W., Kang, Sang-Moo, Prausnitz, Mark R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916971/
https://ncbi.nlm.nih.gov/pubmed/20387097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0134-6
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