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Binding of RBP-Jκ (CSL) Protein to the Promoter of the Kaposi’s Sarcoma-Associated Herpesvirus ORF47 (gL) Gene Is a Critical but Not Sufficient Determinant of Trans-activation by ORF50 Protein

ORF50 protein activates KSHV lytic cycle. The promoter of an early lytic cycle gene ORF47, encoding envelope protein gL, is activated by an interaction between ORF50 protein and RBP-Jκ. In ORF47p only one of two sequences fitting the consensus RBP-Jκ recognition site strongly binds RBP-Jκ and confer...

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Bibliografiset tiedot
Päätekijät: Chang, Pey-Jium, Boonsiri, Joseph, Wang, Shih-Shan, Chen, Li-Yu, Miller, George
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823930/
https://ncbi.nlm.nih.gov/pubmed/20006367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.11.022
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