Regulation of the Abundance of Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2

The switch between latency and the lytic cycle of Kaposi’s sarcoma-associated herpesvirus (KSHV) is controlled by the expression of virally encoded ORF50 protein. Thus far, the regulatory mechanism underlying the protein stability of ORF50 is unknown. Our earlier studies have demonstrated that a pro...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Chang, Tzu-Hsuan, Wang, Shie-Shan, Chen, Lee-Wen, Shih, Ying-Ju, Chang, Li-Kwan, Liu, Shih-Tung, Chang, Pey-Jium
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047794/
https://ncbi.nlm.nih.gov/pubmed/27698494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005918
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