Regulation of the Abundance of Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2

The switch between latency and the lytic cycle of Kaposi’s sarcoma-associated herpesvirus (KSHV) is controlled by the expression of virally encoded ORF50 protein. Thus far, the regulatory mechanism underlying the protein stability of ORF50 is unknown. Our earlier studies have demonstrated that a pro...

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Dettagli Bibliografici
Pubblicato in:PLoS Pathog
Autori principali: Chang, Tzu-Hsuan, Wang, Shie-Shan, Chen, Lee-Wen, Shih, Ying-Ju, Chang, Li-Kwan, Liu, Shih-Tung, Chang, Pey-Jium
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047794/
https://ncbi.nlm.nih.gov/pubmed/27698494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005918
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