Regulation of the Abundance of Kaposi’s Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2

The switch between latency and the lytic cycle of Kaposi’s sarcoma-associated herpesvirus (KSHV) is controlled by the expression of virally encoded ORF50 protein. Thus far, the regulatory mechanism underlying the protein stability of ORF50 is unknown. Our earlier studies have demonstrated that a pro...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Chang, Tzu-Hsuan, Wang, Shie-Shan, Chen, Lee-Wen, Shih, Ying-Ju, Chang, Li-Kwan, Liu, Shih-Tung, Chang, Pey-Jium
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047794/
https://ncbi.nlm.nih.gov/pubmed/27698494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005918
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