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Binding of RBP-Jκ (CSL) Protein to the Promoter of the Kaposi’s Sarcoma-Associated Herpesvirus ORF47 (gL) Gene Is a Critical but Not Sufficient Determinant of Trans-activation by ORF50 Protein
ORF50 protein activates KSHV lytic cycle. The promoter of an early lytic cycle gene ORF47, encoding envelope protein gL, is activated by an interaction between ORF50 protein and RBP-Jκ. In ORF47p only one of two sequences fitting the consensus RBP-Jκ recognition site strongly binds RBP-Jκ and confer...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823930/ https://ncbi.nlm.nih.gov/pubmed/20006367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.11.022 |
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