HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1

Metastasis leads to the death of most cancer patients, and basal breast cancer is the most aggressive breast tumor type. Metastasis involves a complex cell migration process dependent on cytoskeletal remodeling such that targeting such remodeling in tumor cells could be clinically beneficial. Here w...

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Detalhes bibliográficos
Main Authors: Quintela-Fandino, Miguel, Arpaia, Enrico, Brenner, Dirk, Goh, Theo, Yeung, Faith Au, Blaser, Heiko, Alexandrova, Roumiana, Lind, Evan F., Tusche, Mike W., Wakeham, Andrew, Ohashi, Pamela S., Mak, Tak W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823890/
https://ncbi.nlm.nih.gov/pubmed/20133759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914492107
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