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Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer’s Disease

Adult neurogenesis regulates plasticity and function in the hippocampus, which is critical for memory and vulnerable to Alzheimer’s disease (AD). Promoting neurogenesis may improve hippocampal function in AD brains. However, how amyloid β (Aβ), the key AD pathogen, affects the development and functi...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sun, Binggui, Halabisky, Brian, Zhou, Yungui, Palop, Jorge J., Yu, Guiqiu, Mucke, Lennart, Gan, Li
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823799/
https://ncbi.nlm.nih.gov/pubmed/19951690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.10.003
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