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Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer’s Disease

Adult neurogenesis regulates plasticity and function in the hippocampus, which is critical for memory and vulnerable to Alzheimer’s disease (AD). Promoting neurogenesis may improve hippocampal function in AD brains. However, how amyloid β (Aβ), the key AD pathogen, affects the development and functi...

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Detalhes bibliográficos
Main Authors: Sun, Binggui, Halabisky, Brian, Zhou, Yungui, Palop, Jorge J., Yu, Guiqiu, Mucke, Lennart, Gan, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823799/
https://ncbi.nlm.nih.gov/pubmed/19951690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.10.003
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