Neutrophils Are Resistant to Yersinia YopJ/P-Induced Apoptosis and Are Protected from ROS-Mediated Cell Death by the Type III Secretion System

BACKGROUND: The human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp. subvert the innate immune response to cause disease in humans. In particular, the Yersinia outer...

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Hlavní autoři: Spinner, Justin L., Seo, Keun Seok, O'Loughlin, Jason L., Cundiff, Jennifer A., Minnich, Scott A., Bohach, Gregory A., Kobayashi, Scott D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823771/
https://ncbi.nlm.nih.gov/pubmed/20174624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009279
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