Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples

BACKGROUND: In the last ten years, deficiencies in tricarboxylic acid cycle (TCAC) enzymes have been shown to cause a wide spectrum of human diseases, including malignancies and neurological and cardiac diseases. A prerequisite to the identification of disease-causing TCAC enzyme deficiencies is the...

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Autors principals: Goncalves, Sergio, Paupe, Vincent, Dassa, Emmanuel P, Brière, Jean-Jacques, Favier, Judith, Gimenez-Roqueplo, Anne-Paule, Bénit, Paule, Rustin, Pierre
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Methodology article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823639/
https://ncbi.nlm.nih.gov/pubmed/20109171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-11-5
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